Medical Office Space in San Diego.
San Diego medical offices cluster in Kearny Mesa, Hillcrest and La Jolla, around Sharp, UC San Diego Health, Scripps, Kaiser and Rady Children's hospitals.
San Diego Healthcare Real Estate Market
San Diego has 1,419,531 residents (California Department of Finance, 2026), and its medical office space is spread across several hospital districts rather than one core. In Kearny Mesa, Sharp Memorial Hospital (7901 Frost St), Sharp Mary Birch Hospital for Women & Newborns (3003 Health Center Dr), Rady Children's Hospital (3020 Children's Way) and Kaiser Permanente's Clairemont Mesa hospital (9455 Clairemont Mesa Blvd) all sit in the 92123 ZIP code. Hillcrest is home to UC San Diego Health's Hillcrest Medical Center (200 W. Arbor Dr) and Scripps Mercy Hospital San Diego (4077 Fifth Ave), with UC San Diego outpatient buildings on First Avenue, Front Street and Lewis Street. In La Jolla, UC San Diego Health's Jacobs Medical Center campus spans Campus Point Drive and Medical Center Drive, Scripps Memorial Hospital La Jolla (9888 Genesee Ave) has opened a 420,000-square-foot North Tower, and Scripps Green Hospital is attached to Scripps Clinic Torrey Pines. Farther east, Kaiser's Zion hospital (4647 Zion Ave) and UC San Diego Health East Campus Medical Center (6655 Alvarado Rd), bought from Prime Healthcare in December 2023 for $200 million, serve eastern San Diego. Rady Children's Hospital became part of Rady Children's Health when its merger with Children's Hospital of Orange County closed in January 2025. For a practice, the first decision is which health system and hospital district your referrals come from.
Profile updated
Where Medical Offices Cluster in San Diego
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Kearny Mesa (Frost St & Health Center Dr)
Sharp Memorial Hospital (7901 Frost St), Sharp Mary Birch Hospital for Women & Newborns (3003 Health Center Dr), Rady Children's Hospital (3020 Children's Way) and Kaiser's hospital at 9455 Clairemont Mesa Blvd.
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Hillcrest (W. Arbor Dr & Fifth Ave)
UC San Diego Health Hillcrest Medical Center (200 W. Arbor Dr) and Scripps Mercy Hospital San Diego (4077 Fifth Ave); UC San Diego outpatient offices at 4250 First Ave, 4168 Front St and 330 Lewis St.
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La Jolla & UTC (Campus Point Dr, Genesee Ave)
UC San Diego Health's Jacobs Medical Center campus, including the Koman Family Outpatient Pavilion (9400 Campus Point Dr); Scripps Memorial Hospital La Jolla (9888 Genesee Ave); Scripps Green Hospital and Scripps Clinic (10666 N. Torrey Pines Rd).
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Sorrento Mesa
Sharp Rees-Stealy Sorrento Mesa (10243 Genetic Center Dr), a multispecialty center with urgent care, lab, radiology and specialty clinics.
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Eastern San Diego (Alvarado Rd & Zion Ave)
UC San Diego Health East Campus Medical Center (6655 Alvarado Rd), formerly Alvarado Hospital, and Kaiser Permanente's Zion hospital (4647 Zion Ave).
Major Health Systems
- • Sharp HealthCare (Sharp Memorial, Sharp Mary Birch)
- • UC San Diego Health (Hillcrest, Jacobs Medical Center, East Campus)
- • Scripps Health (Scripps Mercy San Diego, Scripps Memorial La Jolla, Scripps Green)
- • Kaiser Permanente (Clairemont Mesa and Zion hospitals)
- • Rady Children's Health (Rady Children's Hospital San Diego)
Neighboring Markets
Current Listings in San Diego
As of October 8, 2026
No active listings in San Diego at this time.
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No case studies for San Diego currently available.
Browse all projectsFrequently Asked Questions
View All FAQs? Where are the main medical office districts in San Diego?
San Diego's medical offices follow its hospitals. Kearny Mesa has Sharp Memorial, Sharp Mary Birch, Rady Children's and a Kaiser hospital, all in the 92123 ZIP code. Hillcrest has UC San Diego Health Hillcrest and Scripps Mercy Hospital, plus UC San Diego outpatient buildings on First Avenue and Front Street. La Jolla has UC San Diego's Jacobs Medical Center campus on Campus Point Drive, Scripps Memorial La Jolla on Genesee Avenue and Scripps Green Hospital with Scripps Clinic on North Torrey Pines Road. Eastern San Diego has Kaiser's Zion hospital and UC San Diego Health East Campus.
? What is UC San Diego Health East Campus Medical Center?
It is the former Alvarado Hospital at 6655 Alvarado Road, a 302-bed hospital that UC San Diego Health bought from Prime Healthcare for $200 million in December 2023. UC San Diego Health announced a new emergency department, a remodeled intensive care unit and expanded behavioral health services, including plans for a dedicated psychiatric care tower. The purchase gave UC San Diego Health a hospital in eastern San Diego, near La Mesa and El Cajon, alongside its Hillcrest and La Jolla campuses.
? Which hospitals are in Kearny Mesa?
Kearny Mesa has four hospitals close together. Sharp Memorial Hospital at 7901 Frost Street is licensed for 656 beds, and Sharp Mary Birch Hospital for Women & Newborns is next door at 3003 Health Center Drive. Rady Children's Hospital, licensed for 478 beds, is at 3020 Children's Way and is now part of Rady Children's Health after its January 2025 merger with Children's Hospital of Orange County. Kaiser Permanente's 253-bed hospital is at 9455 Clairemont Mesa Boulevard. Because three health systems share one ZIP code here, Kearny Mesa suits practices that refer to more than one system.
? Should I lease space near a hospital?
Hospital proximity offers advantages including referral relationships, shared patient populations, and perceived prestige. However, hospital-adjacent properties often command premium rents. Consider whether your specialty benefits from hospital proximity (surgeons, specialists) or whether a community location might better serve your patient base (primary care, pediatrics, dentistry).
? What is a "medical corridor" or "healthcare district"?
Medical corridors or healthcare districts are geographic areas with high concentrations of healthcare facilities, often anchored by hospitals. Locating within these areas can provide benefits including patient convenience, referral network proximity, shared parking arrangements, and established wayfinding. The Bay Area has several prominent medical corridors in cities like Palo Alto, San Jose, and San Francisco.
? What factors influence medical office rents in California?
Medical office rents vary with location (proximity to hospitals and medical corridors), building quality and age, the condition of the space (second-generation medical space with existing exam rooms and plumbing typically leases for more than shell space), lease structure (NNN versus full-service gross), the tenant improvement allowance offered, parking availability, and local supply. Rents also tend to be higher in supply-constrained markets such as Palo Alto and San Francisco than in suburban markets.
Sources
- California Department of Finance, E-1 City Population Estimates (Jan. 1, 2026)
- UC San Diego Health: locations (Hillcrest and La Jolla buildings)
- UC San Diego Today: UC San Diego Health completes acquisition of Alvarado Hospital (Dec. 2023)
- Sharp HealthCare: Sharp Memorial Hospital
- Scripps Health: Scripps Memorial Hospital La Jolla North Tower
- HCAI: Kaiser Foundation Hospital San Diego, Clairemont Mesa
- Rady Children's Health: CHOC and Rady Children's merger closes (Jan. 2025)
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