Medical Office Space in San Francisco.
San Francisco medical office space clusters around UCSF, Sutter CPMC and Kaiser campuses, with new hospitals rising at Parnassus and Mission Bernal.
San Francisco Healthcare Real Estate Market
San Francisco, with about 845,700 residents (California Department of Finance, 2026), has one of the densest concentrations of hospitals in California, and its medical office space clusters around those campuses. UCSF Health operates at Parnassus Heights, Mission Bay and Mount Zion, and in August 2024 it acquired Saint Francis Memorial and St. Mary's Medical Center from Dignity Health, since renamed UCSF Health Hyde Hospital and UCSF Health Stanyan Hospital. Sutter Health's California Pacific Medical Center opened its 274-bed Van Ness campus in 2019 and now runs its Pacific Heights site at 2333 Buchanan Street as an outpatient center. Kaiser Permanente's San Francisco Medical Center sits on Geary Boulevard, and Mission Bay has grown into an outpatient hub with UCSF's Bayfront Medical Building (2024) and Kaiser's Mission Bay Medical Offices at 1600 Owens Street. Two large projects are under way: UCSF's $4.3 billion Helen Diller Hospital at Parnassus (planned for 2030) and Sutter's $442 million neuroscience complex at CPMC Mission Bernal (planned for 2028). Downtown, 450 Sutter Street, a 1929 landmark tower near Union Square, is largely occupied by medical and dental practices.
Profile updated
Where Medical Offices Cluster in San Francisco
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Parnassus Heights
UCSF's main campus, where the 15-story Helen Diller Hospital is under construction (planned for 2030).
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Van Ness Ave / Cathedral Hill & Pacific Heights
CPMC's Van Ness hospital (1101 Van Ness, opened 2019) and its Pacific Heights outpatient center at 2333 Buchanan St.
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Geary Boulevard
Kaiser Permanente San Francisco Medical Center (2425 Geary) and its medical office building at 2238 Geary.
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Mission Bay
UCSF's Bayfront Medical Building (opened 2024) and Kaiser's Mission Bay Medical Offices at 1600 Owens St.
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Union Square
450 Sutter Street, a 1929 landmark tower whose tenants are largely medical and dental practices.
Major Health Systems
- • UCSF Health (Parnassus, Mission Bay, Mount Zion, Hyde and Stanyan hospitals)
- • Sutter Health / California Pacific Medical Center (Van Ness, Mission Bernal, Davies)
- • Kaiser Permanente San Francisco Medical Center
- • Zuckerberg San Francisco General Hospital
- • Chinese Hospital
Neighboring Markets
Current Listings in San Francisco
As of October 10, 2026
No active listings in San Francisco at this time.
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No case studies for San Francisco currently available.
Browse all projectsFrequently Asked Questions
View All FAQs? Where are San Francisco's main medical office clusters?
Medical space concentrates around the city's hospital campuses: UCSF at Parnassus Heights, Mission Bay and Mount Zion; CPMC's Van Ness campus and its Pacific Heights outpatient center at 2333 Buchanan Street; and Kaiser along Geary Boulevard. In Mission Bay, UCSF's Bayfront Medical Building and Kaiser's offices at 1600 Owens Street anchor outpatient care. Downtown, the 1929 tower at 450 Sutter Street near Union Square is largely occupied by medical and dental practices.
? What major hospital projects are under way in San Francisco?
UCSF began building the $4.3 billion, 15-story Helen Diller Hospital at Parnassus in 2024, with opening planned for 2030. Sutter broke ground in June 2025 on a $442 million, 129,000-square-foot neuroscience complex at CPMC Mission Bernal, set to open in 2028 with an on-site surgery center. UCSF also acquired Saint Francis and St. Mary's hospitals in August 2024, renamed them UCSF Health Hyde and Stanyan Hospitals, and announced a $430 million investment across both.
? Which health systems operate hospitals in San Francisco?
UCSF Health runs hospitals at Parnassus, Mission Bay and Mount Zion plus the Hyde and Stanyan hospitals it acquired in 2024. Sutter Health's California Pacific Medical Center operates the Van Ness, Mission Bernal and Davies campuses. Kaiser Permanente runs its San Francisco Medical Center on Geary Boulevard, and the city also has Zuckerberg San Francisco General Hospital and Chinese Hospital. The right location for a practice usually follows its hospital privileges and referral relationships.
? What factors influence medical office rents in California?
Medical office rents vary with location (proximity to hospitals and medical corridors), building quality and age, the condition of the space (second-generation medical space with existing exam rooms and plumbing typically leases for more than shell space), lease structure (NNN versus full-service gross), the tenant improvement allowance offered, parking availability, and local supply. Rents also tend to be higher in supply-constrained markets such as Palo Alto and San Francisco than in suburban markets.
? What parking ratio do medical offices need?
Medical offices typically require higher parking ratios than general office space due to patient turnover throughout the day. A common standard is 5-6 spaces per 1,000 square feet, compared to 3-4 for general office. High-volume practices like urgent care or imaging centers may need even more. Verify the property's parking allocation before signing a lease.
? Should I lease space near a hospital?
Hospital proximity offers advantages including referral relationships, shared patient populations, and perceived prestige. However, hospital-adjacent properties often command premium rents. Consider whether your specialty benefits from hospital proximity (surgeons, specialists) or whether a community location might better serve your patient base (primary care, pediatrics, dentistry).
Sources
- California Department of Finance, E-1 City Population Estimates (Jan. 1, 2026)
- Healthcare Dive: UCSF acquires two Dignity Health hospitals (2024)
- UCSF: construction starts on new Parnassus hospital (May 2024)
- UCSF: Bayfront Medical Building first year (2025)
- Sutter Health: Mission Bernal neuroscience complex
- Sutter Health: CPMC Pacific Heights Outpatient Center
- Kaiser Permanente: San Francisco Medical Center
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